ea0041ep134b | Bone & Osteoporosis | ECE2016
Leclerc Marion
, Benomar Kanza
, Lion George
, Douillard Claire
, Vigouroux Corinne
, Pigny Pascal
, Vantyghem Marie-Christine
Bone is involved in both phosphate-calcium and energetic metabolism. Osteocalcin, secreted by the osteoblasts, stimulates insulin secretion and improves insulin sensitivity. FGF-23, secreted by the osteoclasts, increases phosphate urinary excretion and is a marker of insulin resistance. Relationship between insulin-resistance, body fat and bone metabolism remains unclear. Therefore, the aim of this study was to evaluate osteocalcin and FGF-23 levels in diseases differing by bo...